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Oncology - Tissue biopsy
PANAMutyper™ Screening Kit ROS1
The PANAMutyper™ ROS1 Screening Kit is intended as an aid for screening ROS1 fusion-positive NSCLC patients who would be sensitive for receiving ROS1 inhibitor therapy such as crizotinib, Lorlatinib, etc.
DETAILS
The PANAMutyper™ ROS1 Screening Kit is an invitro diagnostic device for detecting 20 different ROS1 fusion genes of formalin-fixed paraffin-embedded (FFPE) tissue fresh, tissues and biopsy tissues from non-small cell lung cancer (NSCLC) patients.
no. | ROS1 Fusion Types | Partner last observed exon | ROS1 first observed exon |
1 | CD6-R32 | CD74 exon 6 | exon 32 |
2 | CD6-R34 | exon 34 | |
3 | EZ10-R34 | EZR exon 10 | exon 34 |
4 | SL4-R32 | SLC34A2 exon 4 | exon 32 |
5 | SL4-R34 | exon 34 | |
6 | SL13del-R32 | SLC34A2 exon 13del | exon 32 |
7 | SL13del-R34 | exon 34 | |
8 | SD2-R34 | SDC4 exon 2 | exon 32 |
9 | SD2-R34 | exon 34 | |
10 | SD4-R32 | SDC4 exon 4 | exon 32 |
11 | SD4-R34 | exon 34 | |
12 | TP2-R35 | TPM3 exon 2 | exon 35 |
13 | TP2-R36 | exon 36 | |
14 | TP8-R35 | TPM3 exon 8 | exon 35 |
15 | TP8-R36 | exon 36 | |
16 | GO4-R35 | GOPC exon 4 | exon 35 |
17 | GO4-R36 | exon 36 | |
18 | GO8-R35 | GOPC exon 8 | exon 35 |
19 | GO8-R36 | exon 36 | |
20 | LR16-R35 | LRIG3 exon 16 | exon 35 |
FEATURES
- 01One-step RT-PCR technology
- 02Detection of 20 ROS1 fusion gene variants in two tube reaction
- 03High sensitivity, specificity and reproducibility
- 04Short running time
- 05Simple workflow
- 06Easy result reading by automatic analyzing program
PROCEDURE
- Extraction of total RNA
- PCR preparation
- Real-time PCR(RT)
- Analysis of result
COMPATIBLE SAMPE TYPE
Fresh tissue and biopsy
COMPATIBLE Real-Time PCR machine
-
CFX96
(Bio-Rad) -
QuantStudio5
(Thermo Fisher Scientific)